Deadpool and the current Venom, Flash Thompson are team-mates in the Thunderbolts.
As an enemy: That idiot Mac Gargan and Normie's T-Bolts tried to kill me... EPIC FAIL
As a friend: Team-mates in the Thunderbolts with Flash Thompson, Venom's current host, not a huge fan of Captain Hero-Worship, but he has proved to be a total bad-@$$, so I will keep the jock army boy on my "do not kill" list.
Eddie (the speedo thief) Brock: Roomies in some dimension or another, never met in the good ol' 616.
Personally I am dieing for the reunion of Brock/Venom... NOW THAT IS A TEAM-UP WORTHY OF POOL! Heh heh, but seriously, Flash and Gargan need to sit being Venom out, I have heard great things about this Brock guy from Spidey and Wolvie.