Utopia became the X-Men's new homebase after they were threatened in San Francisco, their earlier home. Deadpool visited the X-Men there in an attempt to join them but failed.
He later returned to the island when Selene was attacking them. There, Wade fought the Acolytes together with the young mutant Loa.
Wade visited Utopia in the following comics:
X-Force Annual #1 (2010)